DNA Test: Celiac disease
New: 2 tests in 1, to be done at home in complete comfort.
DNA test specific for celiac disease.
The genetic test, or DNA test, consists of a buccal swab or the removal of the oral mucosa to be carried out by swiping the swab, which you will find around the package, under the tongue or inside the cheek.
DNA testing is very simple and fast. Once the sample has been taken, simply communicate the presence of the sample ready to be sent to the number that you will find in the instructions inside the package and you will be contacted by a courier to collect it.
The report will be emailed to you within 15 days.
Celiac disease, or autoimmune enteropathy from gluten, is a permanent intolerance to gluten contained in wheat, barley, spelled, rye and oat flour. The genetic test allows the diagnosis of celiac disease.
The main genetic risk factors are represented by specific haplotypes (allelic combinations) of the class II HLA genes of the major histocompatibility complex (HLA-DQ2 and HLA-DQ8). DQ2 and DQ8 are glycoproteins, formed by two chains (alpha and beta) encoded respectively by the genes DQA1 and DQB1. The DQA1 * 05 and DQB1 * 02 alleles code for DQ2 with a higher risk of celiac disease, while the DQA1 * 03 and DQB1 * 03: 02 alleles for DQ8 with a lower risk of celiac disease.
Correct collection of the oral mucosa sample requires cleaning of the oral cavity (brushing your teeth or rinsing your mouth a few minutes earlier) to avoid food residues that could stick to the swab.
The test can also be performed on infants.