DNA Test: Lactose + Celiac Disease + Vit. D
New: 3 tests in 1, to be done at home in complete comfort.
Specific DNA test for lactose intolerance, for celiac disease and for the correct assimilation of vitamin D.
The genetic test, or DNA test, consists of a buccal swab or the removal of the oral mucosa to be carried out by swiping the swab, which you will find around the package, under the tongue or inside the cheek.
DNA testing is very simple and fast. Once the sample has been taken, simply communicate the presence of the sample ready to be sent to the number that you will find in the instructions inside the package and you will be contacted by a courier to collect it.
The report will be emailed to you within 15 days.
Find out your physical condition and predisposition to intolerance to milk and dairy products. The genetic test is a valid diagnostic tool for lactose intolerance if accompanied by the typical symptoms of intolerance.
The test allows to discriminate the C / T polymorphism in position 13910, i.e. if in the lactase gene (LCT), on chromosome 2, the copies of the gene are healthy (genotype T / T -> no intolerance), if it has undergone a mutation (genotype T / C -> no intolerance) or if it has undergone both mutations (genotype C / C, homozygosity -> lactose intolerance).
Features of the Lactosolution lactose intolerance genetic test:
- Ability to do it at home, when you are more comfortable and at the time you want
- High sensitivity (97%) or very low probability of false negatives
- High specificity (95%) or low probability of false positives
- Quick and easy to perform, also suitable for children and babies
- It does not cause disturbances
- Complementary to Breath Test C13 or Breath Test H2
Celiac disease, or autoimmune enteropathy from gluten, is a permanent intolerance to gluten contained in wheat, barley, spelled, rye and oat flour. The genetic test allows the diagnosis of celiac disease.
The main genetic risk factors are represented by specific haplotypes (allelic combinations) of the class II HLA genes of the major histocompatibility complex (HLA-DQ2 and HLA-DQ8). DQ2 and DQ8 are glycoproteins, formed by two chains (alpha and beta) encoded respectively by the genes DQA1 and DQB1. The DQA1 * 05 and DQB1 * 02 alleles code for DQ2 with a higher risk of celiac disease, while the DQA1 * 03 and DQB1 * 03: 02 alleles for DQ8 with a lower risk of celiac disease.
Vitamin D performs important biological functions in our body, promotes intestinal and renal absorption of calcium and is essential for the development and maintenance of bone mass. Discover your individual ability to assimilate and use the vitamin D contained in food, influencing the biological processes controlled by it.
For vitamin D, the vitamin D receptor (VDR) is investigated, which is involved in homeostasis and calcium absorption and is involved in bone mineralization. The TaqI polymorphism of the VDR gene, located in exon 9, consists of a nucleotide variation T / C in position -352. The mutation compromises the metabolism of vitamin D and involves an increase in the turnover of bone cells with a consequent increase in the risk of osteoporosis especially in subjects with the C / C genotype.
Correct collection of the oral mucosa sample requires cleaning of the oral cavity (brushing your teeth or rinsing your mouth a few minutes earlier) to avoid food residues that could stick to the swab.
The test can also be performed on infants.
Further information about the genetic test for lactose intolerance can be found in the following article of our BLOG: https://www.lactosolution.com/single-post/2017/07/20/Il-Test-Genetico-per-lintolleranza -al-lactose